Brainstem hypoperfusion in CFS

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Brainstem hypoperfusion in CFS.

Sir, Costa and his colleagues {QJ Med 1995; 88:767-73) are to be congratulated for providing more information about chronic fatigue syndrome. Hypocapnia is a powerful and readily available cerebral vasoconstrictor. 1 The 'cerebral vasoconstric-tion, and reduction in cerebral blood flow, are initiated when the arterial pCO 2 has fallen 2 mmHg below normal. When the pCO 2 has fallen by 25 mmHg, c...

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Brainstem perfusion in CFS.

Sir, Differences of opinion uncover opportunities for research, and so I do not regret my inability to accept the letter from Dr Costa and his colleagues as an answer to my comments. I agree that mild and moderate hyperventilation can produce vasoconstriction, whereas severe and prolonged hypocapnia does not. Lum has given the reason: in minor respiratory alkalosis the neurone is stimulated, bu...

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ژورنال

عنوان ژورنال: QJM

سال: 1996

ISSN: 1460-2725,1460-2393

DOI: 10.1093/qjmed/89.2.163